Lower birth weight is associated with alterations in dietary intake in adolescents independent of genetic factors: A twin study.
نویسندگان
چکیده
BACKGROUND & AIMS Lower birth weight is associated with an increased risk of cardiovascular and metabolic disease. These associations may, at least in part, be explained by alterations in dietary intake in later life. The aim of this study is to examine whether lower birth weight is associated with alterations in dietary intake in later life, and whether this association is due to intrauterine environmental or genetic factors. METHODS In this observational study birth weight and dietary intake were investigated in 78 dizygotic (DZ) and 94 monozygotic (MZ) adolescent same-sex twin subjects. Birth weight was obtained from the mothers. Dietary intake was assessed by two-day dietary records. RESULTS In the total group of twins, lower birth weight was associated with higher intake of saturated fat after adjustment for current weight (1.2 per cent of total energy intake (E%) per kg increase in birth weight, P < 0.01). Intra-pair analysis in all twin pairs demonstrated that twins with the lower birth weight had a 115 kcal higher total energy intake and a 0.7 E% higher saturated fat intake compared to their co-twins with the higher birth weight (P < 0.05). Intra-pair differences in birth weight were negatively associated with differences in energy intake and differences in intake of saturated fat after adjustment for differences in current weight (P = 0.07 and P < 0.05, respectively). Intra-pair differences in birth weight were positively associated with intra-pair differences in intake of dietary fibres (P < 0.05). These intra-pair differences and associations were similar for DZ and MZ twins (P for difference > 0.6). CONCLUSIONS Lower birth weight was related with higher intake of energy and saturated fat within twin pairs, and these associations were independent of zygosity, suggesting that the association between birth weight and alterations in dietary intake in later life is explained by intrauterine environmental rather than genetic factors.
منابع مشابه
تاثیر تعداد وعدههای غذایی در تامین مواد مغذی مورد نیاز نوجوانان
Background: Rapid tissue growth and development during puberty increases the need for energy and nutrients. On the other hand, the prevalence of obesity is accelerating among adolescents. Controversies exist regarding meal frequency, obesity and adequacy of nutrients in particular, a more frequent snacking pattern has been associated with overconsumption of calories in children and adolescents ...
متن کاملشاخصهای پیش بینی کننده عوامل خطر بیماریهای قلبی عروقی در نوجوانان تهرانی: مطالعه قند و لیپید تهران
Background : Cardiovascular disease (CVD) is one of the major health problems in our country. The aim of this study is to determine the predictors of CVD risk factors in adolescents residing in distinct- 13 of Tehran . Materials and methods : Dietary intake assessment was undertaken with 2-day 24-hour recall in 420 adolescents, 11-18 years old, from a total of 15005 subjects participating in Te...
متن کاملDo genetic factors contribute to the association between birth weight and blood pressure?
OBJECTIVES To evaluate whether genetic factors contribute to the association between low birth weight and increased blood pressure among adolescents. DESIGN Historical cohort study of twin pairs. It was evaluated whether (1) a negative association between birth weight and systolic blood pressure was found in the overall twin sample and (2) whether the intrapair difference in birth weight corr...
متن کاملStudy of Factors Affecting Longevity and Survival of Iranian Guilan Sheep Using Linear and Non-Linear Models
The objective of this study was to evaluate non-genetic factors affecting longevity and survival of Guilan sheep from birth to yearling. Longevity and survival records of 41037 lambs born from 496 rams and 10256 ewes of Guilan sheep were analyzed using linear and Weibull models. Results indicated that the overall mean of longevity was 1260.84 days. The fixed effects of flock, dam age, sex, year...
متن کاملEtiology of individual differences in birth weight of twins as a function of maternal smoking during pregnancy.
Birth weight is in large extent influenced by gestational age. In addition genetic and environmental factors determine intrauterine growth and birth weight. The contributions of these factors may be influenced by maternal smoking during pregnancy. We examined birth weight and maternal smoking in a sample of 2930 twin pairs from the Netherlands Twin Register using structural equation modelling. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical nutrition
دوره 36 1 شماره
صفحات -
تاریخ انتشار 2017